Skip to main content
Skip to main navigation
Skip to search

Hisako Masuda
Hisako Masuda,  Ph.D.
Assistant Professor of Biochemistry

Research

Research Interests: Cellular Physiology of Bacteria and Environmental Microbiology. Interests include elucidation of biodegradation pathways for organic pollutants, isolation of novel organic pollutant degrading bacteria, microbial genome analysis, bacterial stress response, microbial motility, enzyme kinetics, and in vivo single molecule tracking. I am also interested in microbial ecology, evolution and bioinformatics.

I utilize many different approaches from molecular genetics, proteomics, biochemistry and bioinformatics to answer intriguing questions such as:

  • Bacterial biodegradation of environmental contaminants
    • Masuda H, Shiwa Y, Yoshikawa H, Zylstra GJ. 2014. The draft genome sequence of the versatile alkane-degrading bacterium Aquabacerium sp. strain NJ1. Genome announcement; 2(6). pii: e01271-14.
    • Masuda H, McClay K, Steffan J, and Zylstra GJ. 2012. Biodegradation of tetrahydrofuran and 1,4-dioxane by soluble diiron monooxygenase in Pseudonocardia sp. strain ENV478. J Mol Microbiol Biotechnol. 22(5): 312-6.
    • Fournier D, Hawari J, Halasz A, Streger, SH, McClay K, Masuda H, and Hatzinger, PB. 2009. Aerobic biodegradation of N-nitrosodimethylamine by the propanotroph Rhodococcus ruber ENV425. Appl Envir Microbiol. 15:5088.
    • Vainberg S, McClay K, Masuda H, Root D, Condee C, Zylstra GJ, and Steffan RJ. 2006. Biodegradation of Ether Pollutants by Pseudonocardia sp. Strain ENV478. Appl Envir Microbiol. 72:5218.
  • Bacterial stress response (Toxin-antitoxin systems)
    • Masuda H., N. Awano, and M. Inouye. 2016. ydfD Encodes a Novel Lytic Protein in Escherichia coli. FEMS Micro Lett 363(6). pii: fnw039.
    • Lin CY, Awano N, Masuda H, Park JH, Inouye M 2013. Transcriptional repressor HipB regulates the multiple promoters in Escherichia coli. J Mol Microbiol and Biotechnol 23(6): 440-7.
    • Masuda H, Tan Q, Awano N, Yamaguchi Y, Inouye M. 2012. A novel membrane bound toxin for cell division, CptA (YgfX), inhibits polymerization of cytoskeleton proteins, FtsZ and MreB in Escherichia coli. FEMS Microbiol lett. 328(2):174-81.
    • Masuda H, Tan Q, Inouye M. 2012. YeeU enhances the bundling of cytoskeltal polymers of MreB and FtsZ, antagonizing the CbtA (YeeV) toxicity in Escherichia coli. Mol Microbiol. 84(5):979-89.
  • Bacterial movements on solid surfaces
    • Cochran C*. and Masuda H. 2015. Switching of the Rotational Direction of Rhizoidal Colonies in a Newly Isolated Bacillus mycoides Strain Ko01. J Gen Appl Micro. 62(2):47-51. *undergraduate student author

To prospective students:

If you are interested in conducting independent research in any of these topics (for credit or not for credit) under my supervision, please contact me via email. We can discuss potential projects and availability. Although the research fully utilizes many concepts and laboratory skills taught in molecular biology (L211) and Biochemistry I and II, please don't hesitate to contact me prior to the completion of these courses. 

Last updated: 08/09/2017